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Quinn Chasan's avatar

Subscribed to comment. I spent a large part of the 2015-2020 era working on the opioid epidemic with state governments. I met with probably 30+ state health directors about modernizing their systems for opioid response.

I've written about my experience drawing a parallel to the MN Feed Our Families fraud (https://open.substack.com/pub/socialdawn/p/the-banal-fraud-of-minnesota) because I think it's a good comparison in some respects.

The truth of the matter is that public health depts in Dem run states were absolutely concerned with cracking down on pill mill drs and clawing funds from bad actors in pharma (good). But then the epidemic moved to hard drugs, synthetics, and fentanyl and with that move the states lost visibility into the problem (bad) and have never fixed it.

They could have turned to law enforcement as a better proxy but they did not. My experience with these states was that they did not take it nearly as seriously as they should have. Public health officials were happy to spend money on a wide range of programs but despite cataclysmic deaths there was a surprising lack of urgency. In New Hampshire, for example, the health agency CIO actually killed the project because of his discomfort in combining healthcare and public health media data in a single analytics system.

The people are not wrong for reacting like this. Cracking down on the criminal supply chain is still an unsolved problem esp at the state level. And once the issue moved out of the neat ICD codes, Medicare SORs, and PDMPs then States lost visibility and really lost interest in solving from the public health agency level.

Seneca Plutarchus's avatar

“The paper finds that higher rates of cancer deaths in 1996 made locations the target of Purdue Pharma’s initial wave of marketing, which led to significantly higher deaths, reliance on public assistance and social insurance programs, and a rising Republican share of the vote””

Aren’t they just finding older, poorer areas? Cancer death rates correlate with age and I’m going to guess inversely correlate with socioeconomic status.

The pain control push was a nationwide affair and it was pushed strongly into the medical system. Only some places fell into the throes of full blown opioid crisis, and it seems like those were the places that were already ground down by other problems and would likely undergo a shift anyway. The Rust Belt was going Republican / grievance politics before the opioid epidemic and likely didn’t require the epidemic to continue.

It’s been well documented that Republicanism has been having much more success with lower SES individuals, particularly since Trump.

Alex's avatar

The most interesting thing in the paper (and video Jerusalem did on it) is how media covered the epidemic which is where I think the actual causation is happening here. Right wing local media, which filters up to national media was way way more likely to cover the opioid epidemic than left wing local and national media.

So essentially really bad thing happens that fits snuggly into a rightwing narrative about social disorder and decline -> right wing media picks up on it -> those concerned about the opioid epidemic are more likely to align with right wing politicians

also in the paper they point out the people actually suffering from addiction notably didn't get more republican, it was everyone else around the addicts that did. fairly classic case of american left blindness to social disorder opening up opportunities for right wing gain

Kenny Easwaran's avatar

Yeah, that’s what I was going to say. This isn’t that impressive as an argument that the opioids are causal unless you can show that the thing causing the opioids is independent of other relevant factors. How much variance is there in cancer rates that isn’t explained by age and poverty? And even if one county has higher cancer rates caused by a cosmic ray burst or whatever other deus ex machina you want, why think it’s the opioids causing the political change rather than the cancer itself?

ScienceGrump's avatar

I find that people with economics backgrounds tend to be really sharp and alert to flawed causal arguments... except in economics. The basic techniques in this paper for converting correlation into causation are, basically, a bullshit generating engine. The fact that they're standard practice in economics is why economics writ large is a bullshit generating engine. TBC, I can totally believe that opioids made people more Republican, because I buy the larger argument that public disorder drives a conservative authoritarian backlash. I just don't believe that the incredibly contrived pseudorandomization in this white paper - cancer rates in the 90s! - does anything at all to resolve the causal structure and I desperately wish people would stop crediting this approach.

John M's avatar

This is just a standard instrumental variables study. The idea is that if B causes C and you know that A causes B and has no obvious alternative pathways by which it could cause C, then A should have a correlation with C that can be explained by its effect on B. In this case, A is cancer mortality, B is opioid use, and C is political shift.

Of course, this doesn't give you undeniable proof of causation (you can't be sure that A doesn't correlate with C through other means), but it is evidence.

ScienceGrump's avatar

Yes. Instrumental variables studies are exactly what I am describing as bullshit.

- Correlation is not transitive

- There are many unobserved variables with unknown causal relationships to A, B, and C

- Specifically, A (cancer incidence) is not a random variable. It is a function of many variables - average age of the population, primary occupation, smoking, pollution, race - which all have independent relationships with the outcome of interest (political lean). In fact, if it weren't for these variables, cancer incidence would be geographically uniform and there would be nothing to correlate political outcomes with in this paper.

- Even in the event that you had unlimited independent and identically distributed measurements of the full graph, and both the graph and errors happen to satisfy some incredibly strict constraints that don't apply in reality, learning the true Bayesian graph is NP hard: https://jmlr.csail.mit.edu/papers/volume5/chickering04a/chickering04a.pdf

- But we don't have unlimited i.i.d. measurements of the graph.

- The ability to pick your "instrumental" variable gives almost unlimited latitude to the authors to engineer whatever outcome they want. Here, they not only get to choose to use diagnoses of a disease, but which disease (cancer is not actually a natural choice, many more people prescribed opiates for cancer in the 90s would die of their disease than O.D.) and time frame (the 90s???)

All this is without bothering to read the white paper, which I guarantee would reveal additional methodological problems.

LazlowB's avatar

I get where you and Kenny are coming from, and I appreciate the demand for inferential rigor. I think what you've said is right, but I also think it is a bit off to the side of the main point. Apart from how well the paper supports the inference that opioid exposure drove a shift in political leanings, there are somewhat separate and valuable insights here about how the opioid story is discussed and understood on the right vs on the left ... along with the fact that it is far more discussed on the right than on the left.

ScienceGrump's avatar

This is true, but I'm not sure it cuts against the grain of conventional wisdom the way Demsas suggests. The consensus I see is that many swingy Trump 2024 voters were reacting to 1. inflation and 2. public disorder, maybe in that order, maybe not. In particular, I have seen zero people argue that anti-immigrant politics is really just about economics. Not saying no such people exist. I have no doubt you could dig up some leftists saying exactly that. But they are not exactly dominating the discourse.

LazlowB's avatar

Completely agree about what was moving the large numbers of swing voters. Before I read this essay, I didn't see how the opioid crisis mapped onto the Republican/right narratives about crime and public disorder. Maybe I just hadn't thought about it. Either way, I appreciate learning something new. ... and appreciate your input on the methodological points as well.

John M's avatar

Sure, but a priori there is no reason to expect the instrument to have any particular relationship with the outcome. So if it has the relationship predicted by your theory, that is evidence for your theory.

Now, you're right that the ability of researchers to pick the instrument presents the opportunity for bias to seep in, which is why you shouldn't update too much on any given IV finding and always stay open to the possibility of future evidence casting doubt on it. Still, I think you can update on it somewhat, especially if you have mitigations in place like preregistration.

ScienceGrump's avatar

But as I and Kenny pointed out, there are many cancer correlates that are a priori expected to have a relationship with political lean. Age and blue-collar lifestyle are not minor factors in politics. They're like the biggest stories of the political realignment!

And even if we had no a priori expectation about them, the correlation would still only be evidence that some cofactor influenced partisan lean. It still wouldn't tell you anything about the specific cofactor the authors want you to pay attention to.

Kenny Easwaran's avatar

The problem here is that A seems to have *many* obvious pathways by which it could affect C - cancer tends to be correlated with a lot of political-economic variables like age and poverty and types of factories, and cancer itself is a significant life experience that can affect people’s politics (and that of those in their life).

atomiccafe612's avatar

It seems like the macro trend across the whole world is politics being much more sorted by educational attainment and this could easily also cross over to stuff like opioid addictions and cancer as well.

John M's avatar

That's true, but a priori, cancer could have a negative, positive, or null relationship to a particular political ideology. If it has the relationship predicted by your theory, is that not evidence (albeit weak evidence) of your theory?

Kenny Easwaran's avatar

Yeah, I think there’s interesting work to be done to figure out all the pathways by which cancer rates in the mid 90s affect changes in partisanship a few decades later. I just don’t think one can confidently claim that it’s all via opioids. (Though I haven’t read the paper to see what sorts of statistical methods they use to try to rule out alternatives.)

mathew's avatar

Obviously there is only one clear solution then. Get ourselves a selection of several thousand towns, and randomly assign them to a control or experimental group. Then ship free opioids into the towns in the experimental group. Then wait 20 years and look at changes in voters preferences.

ScienceGrump's avatar

Too much variance. People in some towns will be more likely to refuse to take the free drugs. The only solution is to inject it directly into their veins.

mathew's avatar

Maybe ICE can do that

Justlaxin's avatar

I know this isn't really the purview of this post, but how do we make sense of the polling finding that the issue with immigration is crime when we also know that illegal immigrants commit fewer crimes than native citizens?

Like, if we had a magic button that would safely teleport all illegal immigrants currently in the US to their home countries the crime rate in the US would go up...

I realize that the average American is not a perfect machine that feeds knowing all facts directly into their political worldview.

But to your point about having to go through the steps of identifying issues, agreeing that they are the fundamental issue, and then moving on to solutions, what do you do if the problem voters are seeing are...fake or, more politely, incorrect.

Nicholas Weininger's avatar

First, people perceive publicly visible disorder and ugliness as a crime-like threat, and a threat that makes them believe there's more crime around, even when there isn't. And the poor logistical handling of the Biden-era migration surge did produce some of that disorder and ugliness.

Second, racism. People are more inclined to be suspicious of others' possible criminal intentions when those others don't look like them and/or don't speak their language.

As depressing as both of those forms of irrationality are, quoting the statistics about low rates of immigrant crime at people is unlikely to change them. We need people who are good at understanding social-psychological intuitions to devise more effective forms of what one might call "bias interruption".

Justlaxin's avatar

I am very aware of the latter idea. The former makes sense. But it still doesn't totally answer my question (not saying you specifically have to).

In a world where voters demand solutions, this still represents a made up problem. Per my example, removing all illegal immigrants will not fix their stated concern.

Further, while I take the point that disorder roughly equals "crime" in the average person's mind, there is something else going on here. You can see that from how high the anti-immigration sentiment is/was in places with incredibly low levels of both immigration and crime!

NYC unfairly had immigrants literally bused to them. It did increase burden and definitely cause a backlash. But it didn't, like, turn NYC red or anything of the sort.

On the other hand you have people in 99% racially homogenous places with basically zero homelessness or vagrancy (by any race) saying immigration is a huge issue for them...

mathew's avatar

Even if illegal immigrants on average commit less crimes, you would still get more crime because of the increased population.

"Like, if we had a magic button that would safely teleport all illegal immigrants currently in the US to their home countries the crime rate in the US would go up..."

But the TOTAL number of crimes would go down.

Also, the very visible criminal elements seen with the cartels. is a big factor, just like the gang violence problem in urban areas.

Justlaxin's avatar

It is possible there is research that suggest otherwise, but I do not think this is how people's perception of crime works.

Since you mentioned urban areas, let's use such an example and take Chicago. As I understand it, there is a lot of crime in South Side and that a much wealthier area, like Lincoln Park has little crime.

However, there is still crime in the wealthier areas. So if you just...deleted them and left South Side, and neighborhoods like it as the only parts of Chicago left, crime would go down.

But I do not think people would look at a Chicago that is now JUST South Side and say "there is less crime here".

Ben's avatar

This seems like a major flaw in the hiring of political professionals if their skill is supposed to be winning elections. "Time and again, political professionals assume that their frame for understanding an issue is the primary one, stubbornly sticking to an analysis of root causes, only to find out voters are speaking a completely different language."

Sam Penrose's avatar

Great column, thank you. Yglesias makes a related point today about Democratic partisans:

“The way you become mayor of San Francisco and then rise to statewide office in California is by calibrating your appeal to hardcore partisan Democrats, so of course you feel that his vibes are impeccable. A politician whose vibes are attuned to maximizing crossover appeal and winning swing votes probably will not vibe that hard with you, unless you personally are a swing voter.”

https://www.slowboring.com/p/gavin-newsom-is-very-similar-to-kamala

Appropriate Adult's avatar

"The economic frame is the default language of the policy class on both sides." YES!!! I think this almost-exclusive framing is a mistake. Some of us are motivated by factors other than economic, like the good of the whole, not wanting people to suffer, and care for our neighbors.

Regarding opioids, as described by Barbara Kingsolver in Demon Copperhead, a major cause of illegal opioid use is lack of access to emergency medical care. In her story, a character with a broken leg had to wait a month and travel to another state to get his leg set, resulting in opioid addiction to manage the pain during that wait for care. This is unimaginable to those of us who live reasonably near an emergency room; a broken bone will be set within 24 hours. As Medicaid cuts force the closure of hospitals and emergency departments throughout the US we can expect to see more of this.

Austin L.'s avatar

I really enjoyed listening to the podcast this morning. Honestly, at first I wasn’t sure about the correlation between the opioid epidemic and parts of America switching to the Republican Party. However, the explanation of secondary and tertiary effects i’m not only the individuals using the opioids, but also the families and neighbors in the community really hit the point home. I also enjoyed this article explaining other major political issues that need to be thought of in a new way when it comes to understanding why Republicans might be trusted more on their policies to address them.

LazlowB's avatar

I love this post. My favorite essays or articles are the ones that turn the prism a different way and show me something I was missing. I wouldn't have seen it if someone didn't show me. It's an endless process in politics and society. I got my money's worth from The Argument today.

Y. Andropov's avatar

People on welfare use drugs. People who have to work don't.

Auros's avatar
Feb 2Edited

That was true in the '90s, but has not been true for the past ~twenty years.

https://www.clasp.org/press-room/news-clips/welfare-recipients-are-less-likely-be-drug-users-average-american-results-show/

https://www.ebsco.com/research-starters/politics-and-government/drug-testing-welfare-recipients

https://journals.healio.com/doi/10.3928/0279-3695-19970201-13

I can't really support it, but my interpretation of the data is that the folks who are trying to point to this to say that drug-testing of recipients is unfair / unnecessary are being dumb -- that it's the common expectation that drug-testing will be required for welfare that is _causing_ the decline in drug use among recipients, even in states that actually aren't testing. A lot of people who are on drugs, and could use the help, _believe_ they won't be able to get it, and thus don't bother applying.

On the one hand, there is a valid argument that what we really want is for the people on drugs to still seek help, including treatment to break their addictions. On the other hand, the testing seems to be doing exactly what it was intended to do. On the gripping hand, the testing regime as it's currently administered almost certainly costs the state more money than it saves in reduced welfare payments, both directly, and through the indirect cost of causing many people who _aren't_ on drugs to end up losing their welfare, and falling deeper into poverty, where they're more likely to _become_ criminals and/or addicts.

MikeR's avatar

The first article you linked to is pretty much the perfect example of why people don't trust studies like it. The data doesn't say people on welfare use drugs less frequently than those not on welfare; it says that the vast majority of people who applied for one specific form of state administered, federally funded welfare, which they know requires a drug test, were able to pass that drug test. These are two very different things.

Auros's avatar
Feb 5Edited

You're agreeing with my own overall analysis of the studies -- testing is pretty effective at discouraging drug use. The folks who _are_ using don't even bother to apply for programs that test. There's at least some evidence as well that the rise of testing has meant that even programs that aren't testing have seen a decline in how many users are on their rolls.

Big picture, LOTS of people, employed or not, use drugs. Certainly folks with a serious addiction problem are more likely to eventually screw up their lives in ways that lead to losing their employment, but all kinds of people abuse painkillers, or snort coke, or whatever, and go right on working, for _years_. I don't really think at this point that it's in any way useful or accurate to stereotype welfare recipients as being particularly likely to have drug issues. As with homelessness, you definitely find that some of the most _persistently_ homeless have drug or mental health problems. But on any given day, the vast majority of people who count as "homeless" are just down on their luck. They sleep in their cars, or manage to crash on somebody's couch, and don't create visible disorder. Many of them will stop being homeless within a few months. But unfortunately, some of them, _because_ of their homelessness, will _develop_ drug or mental health problems that turn them into longer-term problems for everyone else in the community.

MikeR's avatar
Feb 5Edited

It discourages drug use, but it also diverts users away from those specific programs. TANF is only a minority of welfare payments; it's hard to draw conclusions on the overall impact of drug testing on drug use by welfare recipients across the board. There's also the biggest issue I have with studies revolving around substance abuse-you're dealing with a population that lies habitually, being interviewed by people who don't comprehend that mindset.

Yes, they can be a functional substance abusers for 20 years. People live for longer than that, and that slide gets rough. In the same way it's easy for a 22 year old to party till 3, wake up at 7, and power through a hangover at work the next day, plenty of people can borrow against their twilight years and burn through their savings through the use of narcotics, ending up dead, crippled, and/or broke by 65. Not a great plan, but to each their own.

And your take on homelessness does not, in any way, match what I see on a regular basis. Yes, a lot of people are homeless for very short time periods-none of us are talking about them. Shit, I've been them a couple times in my life. The single biggest risk factor for homelessness-unsheltered transients-is being unpleasant to deal with-through drugs, mental health problems, or general criminality. They've burned through social resources, legal assistance, family ties, and any friends outside of that life. Based on everything I have seen, repeatedly, over the past four years, you have the causation backwards.

Stephen Boisvert's avatar

I don't see how Medicaid should save people from opioid deaths. Locking them in prison is much more effective if you care about “life.”

Kenny Easwaran's avatar

I think it’s quite plausible that medical treatment aimed at getting people off opioids is actually more effective at preventing deaths than locking people in prison. It’s quite well known that there’s a lot of drug use in prison. Of course we would need actual studies to figure out whether the medical treatment is in fact effective, but I think that’s the claim of the article - that studies have in fact found that Medicaid is more effective than prison at preventing overdose deaths.

Stephen Boisvert's avatar

"Fentanyl Crisis: In California, for example, overdose deaths in state prisons dropped slightly from 64 in 2019 to 53 in 2022, but fentanyl seizures in that system increased by over 11,000% between 2019 and 2023."

I think Medicaid is more effective because the effort it takes to sign up indicates a desire to quit. Anything else is secondary to that.

Stephen Boisvert's avatar

(What's key about my somewhat facetious OP is I'm saying never let them out of prison to keep them alive. I think it's undeniable that being confined in the institution of the prison drastically decreases concurrent morbidity.)